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Welcome Debbie's Dream Foundation: Curing Stomach Cancer
Debbie's Dream Foundation: Curing Stomach Cancer is dedicated to raising awareness about stomach cancer, advancing funding for research, and providing education and support internationally to patients, families, and caregivers. DDF seeks as its ultimate goal to make the cure for stomach cancer a reality.
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March 24, 2016 – Technion's Artificial Nose Inventor Makes ‘Good Guy' List

Congratulations to Professor Hossam Haick of the Technion whose research led to technology that can smell out cancer! Professor Haick's contributions to the field have earned him a place in GOOD Magazine's list as one of the 100 most influential people in the world who are changing the world in a positive manner.

January 28, 2016 - Video Intervention Helps Prepare Patients to Participate in Cancer Clinical Trials

A new study shows that educating a patient about clinical trials before he or she seeks an oncologist can improve the patient's decision about whether to join a trial.  Fewer than 5 percent of adult cancer patients participate in a clinical treatment trial.  Two decision-making frameworks will develop an online, video-based educational program in order to assist cancer patients with their options.  Webcasts on various topics affecting stomach cancer patients including clinical trials are available year round in the Lecture Library on the Debbie's Dream Foundation website.

January 7, 2016 - Stomach Cancer: Know These 7 Risk Factors

Increased knowledge of risk factors allows early-stage stomach cancer to be more curable with early detection.  The seven risk factors identified by H. Chung are gender, ethnicity, history of H.pylori or gastritis, genetics, smoking, and diet.  It is crucial to obtain an accurate diagnosis including identifying the stage of cancer.  Proper treatment is also important to improve the quality of life and long-term survival.

August 13, 2015 - ASCO Connection - James Randolph Hillard, MD - DDF Michigan East Chapter Founder Blog

James Randolph "Randy" Hillard, MD is DDF Michigan East Chapter founder and Professor of Psychiatry at the Michigan State University (MSU) Colleges of Medicine. In 2010, he was diagnosed with HER-2, stage IV metastatic gastric cancer, caused by Helicobacter pylori and kept in check, so far, by trastuzumab. He is dedicated to education and advocacy for better prevention, detection, and treatment for stomach cancer.

July 12, 2015 - Top 8 Foods that Help in Fighting Cancer

Nutrition is very important when it comes to keeping our bodies healthy and preventing diseases like stomach cancer. Eight foods that help prevent and/or fight cancer are dark green leafy vegetables, beans, berries, pawpaw and grapes, garlic and ginger, carrots, walnuts, and tomatoes.

June 29, 2015 - Weekly Oraxol for Second-Line Treatment of Metastatic, Recurrent Gastric Cancer

According to Cancer Therapy Advisor, a study was completed to determine the maximum tolerated dose (MTD) of Oraxol and to evaluate the efficacy and safety of the drug as a second-line treatment for metastatic or recurrent gastric cancer. The study found that 9.3% of patients (4 out of 43) achieved a partial response level from treatment and the most common side effects included low white blood cell count and diarrhea.

June 5, 2015 - The 11 Countries with the Highest Rates of Stomach Cancer

According to Insider Monkey, stomach cancer has a high influence on the "11 Countries with the Highest Cancer Rates in the World" list. The eleven countries with the highest stomach cancer rates in the world are Turkmenistan, Belarus, Albania, Kyrgyzstan, Kazakhstan, Tajikistan, China, Guatemala, Japan, Mongolia, and the Republic of Korea.

May 22, 2015 - Stay Away From Processed Foods to Avoid Acid Reflux and Potentially Esophageal Cancer

According to the American Cancer Society, 1% of all cancers are of the esophagus, and 80% of people diagnosed with esophageal cancer live less than five years. Acid reflux is a big risk factor, and 80-90% of esophageal cancer patients have it. In order to prevent acid reflux, one should limit alcohol, carbonated drinks, spicy foods, and caffeine, eat slowly, keep the weight down, don't lay down after eating, and wear comfortable clothing.

May 15, 2015 - New Drug Combination Boosts Survival in Advanced Stomach and Esophageal Cancer

Peter Enzinger, MD of the Dana-Farber Cancer Institute and a DDF Medical Advisory Board Member will present findings of a recent phase 2 trial examining a new drug combination. The study examined the effects of adding bevacizumab to a standard drug combination for HER2 positive patients. Dr. Enzinger will report the findings during the American Society of Clinical Oncology annual meeting on Monday June 1, 2015.

May 5, 2015 - 10 Reasons to Eat an Onion

Onions, a vegetable that is part of the allium group, have many benefits relating to cancer, sleep and mood, skin and hair, anti-inflammatory, infections, fever and allergies, diabetes, acne treatment, and toothache. Onions are a strong source of vitamin C and have been inversely related with the risk of stomach and esophageal cancer.

March 22, 2015 - Statins Promising for Decreased Gastric Cancer Risk

Statins, cholesterol lowering drugs, can have a beneficial health effect involving anti-cancer properties. Out of 6 case-control studies that included 5,993 cases of gastric cancer, a 44% decrease risk of gastric cancer was found with the use of a statin. However, the studies did not prove that the medications were directly responsible for benefits.

March 22, 2015 - Drugs to Treat Hereditary Gastric Cancers Found

Although they have yet to be named, certain existing drugs have been found to effectively treat or prevent hereditary stomach and breast cancers. The Molecular Cancer Therapeutics journal suggests that people suffering from these diseases are expected to have relief in the future. Genomic screening was used to search for vulnerabilities in cancer cells that lack E-cadherin, a tumor-suppressor protein.

March 18, 2015 - Controlling Indigestion Problems

A bloated stomach, shortness of breath, and sweating are all signs of indigestion. Stomach cancer and indigestions share similar symptoms, but stomach cancer can also include heartburn, upper abdominal pain, nausea, and loss of appetite. In order to ensure a healthy digestive system, make sure to eat plenty of fiber, drink plenty of water, chew your food, don't overeat, and exercise and see your doctor.

March 14, 2015 - 9 Useful and Healthy Vegetables to Prevent Stomach Cancer

Certain vegetables, such as cabbage, spinach, paprika, beetroot, broccoli, peas, and onions, can help prevent and be used as a treatment for many diseases. Peas, in particular, can help reduce the risk of stomach cancer.

March 13, 2015 - Southampton General Hospital Is The First In The Country To Host A Special Stomach Cancer Event

Southampton General Hospital has been chosen to host "Super Saturday" events in the UK. "Super Saturday's" purpose is to tackle the rise of stomach and esophageal cancer cases. Endoscopies will be carried out throughout the day; the link between persistent heartburn and difficulty swallowing with stomach and esophageal cancers will be taught.

February 25, 2015 - A Faster Way to Try Many Drugs on Many Cancers

This spring, studies will be conducted to screen tumors in thousands of patients in order to see which might be attacked by at least a dozen new drugs. These studies will be done by a federally funded program, and medical facilities like Memorial Sloan Kettering Cancer Center in New York are ready to find answers to which drugs can stop cancer mutations. Genes and mutations can power cancer growth and make cells spread to different parts of the body.

February 20, 2015 - The True Health Benefits Of Garlic

While fish oil is the most utilized supplement in the United States, garlic comes in second place and is used to prevent and treat illnesses such as stomach cancer, high blood pressure, and diabetes. Allicin is the active health benefit ingredient found in garlic but it can be destroyed while cooking and by stomach acid when ingested. Haru Amagase, Wakungal's director of research and development, advises that coated garlic supplements are the only beneficial way for the supplement to be transported toward the intestines.

February 19, 2015 - First Person in UK to Have Stomach Removed By A Robot

Frank Lawson, a 77 year old gardener and retired engineer, is the first person in the UK to have their stomach removed by a robot due to gastric cancer. This eight and a half hour surgery can lead to better outcomes and a quicker recovery time due to the minimally invasive techniques.

February 19, 2015 - Esophageal and Esophagogastric Junction Cancers

Esophageal cancer is the sixth most common cause of cancer deaths worldwide. The National Comprehensive Cancer Network (NCCN) recently released Guidelines for Esophageal and Esophagogastric Junction (EGJ) Cancers discussing the management of local advanced adenocarcinoma of the esophagus and EGJ. President and Founder of Debbie's Dream Foundation Debbie Zelman contributed to these guidelines as well as members of our Medical Advisory Board: Jaffer Ajani, MD; Charles Fuchs, MD, MPH; David Ilson, MD, PhD; Lawrence Kleinberg, MD; and Mary Mulcahy, MD.

February 18, 2015 - CDH1 Mutations Bring High Gastric Cancer Risk

According to a study published in JAMA Oncology by Samantha Hansford, men who carry the mutation in the E-cadherin (CDH1) gene have a 70% chance of gastric cancer by age 80, while women who carry the gene have a 56% chance of gastric cancer by age 80. E-cadherin (CDH1) is a gene linked to hereditary diffuse gastric cancer. The families used for the study came from multicultural backgrounds and were from regions where gastric cancer rates are low.

February 18, 2015 - Blood Tests Now Identify E-Cadherin Gene in Whanau

The E-cadherin gene affects about 12 whanau Maori, a tribe in New Zealand, and 350 families worldwide. A simple blood test can now tell if the whanau members have the E-cadherin mutation, and it then gives them the option of getting surgery to remove the stomach and risk of getting cancer or taking part in annual checkups to see if the cancer forms.

February 16, 2015 - Eating Carrots Will Keep You Healthy

Carrots not only protect your eyesight, but they also offer protection against cancer. Beta carotene, which is found in carrots, strengthens the immune system and protects the body against cancer and infections. The cooking process helps release more of this important compound.

February 16, 2015 - Weight Is a Breeding Ground For Cancer

Eating healthy, being physically active, and maintaining a healthy weight could prevent one third of cancers. Besides not smoking, maintaining a healthy weight is the most important thing you can do to prevent cancer. In order to maintain a healthy weight, one should eat small amounts of red meat, keep treats sensible, reduce salt intake, limit alcohol, not smoke, take care in the sun, and keep active.

February 13, 2015 - Smoking Kills

Direct smoking, secondhand smoking, chewing tobacco, using pan, and other tobacco products cause various cancers which include stomach cancer. In order to establish a healthy society, teachers, activists, scholars and media will have to play a role in creating awareness and educating people.

February 10, 2015 - Cancer Patients and Doctors Struggle To Predict Survival

Research shows that when patients are told their cancer prognosis, less than half of what the doctor said is retained leading to confusion about survival rates and prognosis. According to Dr. Tomer Levin, of Memorial Sloan Kettering Cancer Center in New York, doctors think of the survival rate they tell patients as a median number, but patients see this number as being concrete and absolute.

February 7, 2015 - World Cancer Day: Foods That Prevent Cancer

World Cancer Day is annually celebrated on February 4th and encourages people to make the right choices when it comes to guarding themselves from cancer. Certain foods, such as processed and red meats, may increase your risk of developing cancer, while other foods, such as fruits and veggies, may help in guarding against and healing cancer.

February 6, 2015 - 10 Cancer Symptoms People Generally Ignore

Some symptoms, such as long lasting sore throat, unexplained weight loss, difficulty swallowing, and bleeding are often ignored due to casual thinking and seasonal patterns. Although they may be minor, these symptoms can be an early sign of cancer, and when addressed, can be treated properly.

January 31, 2015 - S'pore Team Develops Blood Test Cancers

A team of Singaporean scientists from the Agency for Science, Technology and Research have developed a blood test that can detect cancer at its earliest stage, even before symptoms start to appear. This became possible when the team developed a method to measure small changes in gene levels called micro-RNA in blood. This three hour test has achieved more than 90% accuracy in the lab and is planned to be used in hospitals in Singapore in 2017 as a screening tool.

January 26, 2015 - Heartburn Said to be Sign of Stomach or Esophageal Cancer

A new study reveals heartburn for three or more weeks can be a sign of stomach or esophageal cancer. However, only one in two people reported they would visit their doctor if they had heartburn for three or more weeks. Early detection and diagnosis of stomach cancer is critical to more successful treatment outcomes.

January 19, 2015 - Novel MET Inhibitor Elicits 'Dramatic Response' in Gastric and Esophageal Cancers

Preliminary results from a small study examining a small-molecule MET Inhibitor has shown dramatic results in MET-amplified gastric and esophageal cancers. The Chair of the Debbie's Dream Foundation Medical Advisory Board, Dr. Jaffer Ajani, noted that the biomarker and the drug are good and further testing should be pursued.

January 16, 2015 - The Coming Revolution In Much Cheaper Life-Saving Drugs

Randy Hillard, DDF's Michigan East Chapter Founder, understands how expensive stomach cancer infusions can be, so he decided to take matters in his own hands. Randy cast a vote on a Food and Drug Administration panel to recommend the approval of the first in a new class of drugs called "biosimilars." Biosimilars, or biologics, are made from living organisms and can be very complex and costly.

January 16, 2015 - Consume Less Salt to Reduce Stomach Cancer Risk

Not only does a large amount of salt consumption cause high blood pressure, but it may also increase the risk of stomach cancer by encouraging the growth of H. pylori and making cells toxic. The World Health Organization recommends that 5g of salt, which is less than 1 teaspoon, should be the most salt one should have in their diet per day.

January 8, 2015 - 7 Tips For A Successful First Visit To Your Oncologist

It's understandable that you may feel a little nervous or anxious the day of your first visit to your oncologist. Click on the link below to read seven tips for making the most of your first visit and having a successful day.

January 8, 2015 - How to Keep Your Pearly Whites in Top Shape During and after Cancer Treatment

Oral health is not only very important in everyday life, but it is especially important to patients going through chemotherapy. The mouth, gums, and teeth become vulnerable, and dry mouth, also known as xerostomia, can lead to an increased risk for tooth decay. Brushing and flossing frequently, using fluoridated toothpastes and rinses, and getting regular dental checkups are key factors to limiting oral health problems. Sugary foods and drinks may lead to tooth decay, so watching what you eat and brushing after each meal are also important. By taking care of your gums, teeth, and mouth, you'll be able to not only live a healthy lifestyle, but you will also be able to smile with confidence.

January 1, 2015 - 6 Health Benefits of Oranges

Oranges offer many benefits such as boosting energy, lowering cholesterol, and fighting against the common cold. The vitamin C and potassium also found in oranges is good for overall health. Oranges are also rich in citrus limonids, which are proven to fight certain types of cancer including stomach cancer.

December 31, 2014 - Lilly Receives EU Approval For Stomach Cancer Drug Cyramza

Eli Lilly and Company received European regulatory approval for the ramucirumab-based therapy Cyramza, a new treatment for stomach cancer. During phase III trials, the drug showed promising results, such as survival rates and delaying disease progression.

December 30, 2014 - Imugene Hits Milestones On The Road To Her-Vaxx 2015 Clinical Program

According to MENAFN - Proactive Investors, "Her-Vaxx is a proprietary peptide vaccine or immunotherapy that causes the immune system to generate cancer-fighting antibodies." Imugene, the Australian company who created the drug, is ready to start a clinical program for Her-Vaxx, while finalizing the clinical protocol for gastric cancer patients undergoing the Phase Ib/II clinical trial.

December 30, 2014 - Eating More Vegetables Reduces Men's Risk Of Stomach Cancer

An eleven year study by the National Cancer Center in Japan found that men who eat more vegetables have a lower risk of developing distal stomach cancer. On the other hand, women who eat plenty of vegetables do not have the reduced risk as men with stomach cancer.

December 18, 2014 - AstraZeneca's Blockbuster Cancer Drug Gains EU Approval
December 16, 2014 - FDA Grants Orphan Status to Insys' Gastric Cancer Treatment

Insys announced that it has received orphan drug status from the FDA for Liposome Entrapped Paclitaxel Easy to Use (LEP-ETU) for the treatment of advanced gastric cancer. LEP-ETU is a reformulated version of paclitaxel, which has boosted its efficacy and reduced toxicity. Orphan drug designation provides a special status to a drug that treats a rare disease or condition upon request of a sponsor.

December 15, 2014 - Advaxis Announces FDA Acceptance of New Drug Applications

Advaxis is a clinical biotechnology company with a focus on developing cancer immunotherapies. Advaxis is currently working to develop their drug ADXS-cHER2 to target HER2 expressing cancers, such as gastric cancer. ADXS-cHER2 has received orphan drug designation by the FDA for the treatment of osteosarcoma.

December 11, 2014 - Keytruda Effective Against 7 Types Of Cancer And Counting

Merck & Co.'s new drug, Keytruda, is a type of immuno-oncology drug that fights cancer by giving T cells the opportunity to attack hidden cancer cells. Stomach cancer is one of many cancers that Keytruda has a positive testing report.

December 10, 2014 - Imugene Completes $3.5m Capital Raising

Imugene has raised $3.5 million in capital to help pay for trials of its Her-Vaxx anticancer candidate. The funds will be used to manufacture the drug and help fund its Phase Ib/II trial for patients with metastatic gastric cancer.

December 9, 2014 - MatriStem Featured in Annals of Clinical Oncology

MatriStem Surgical Matrix was recently featured in the Annals of Surgical Oncology for reducing the incidence of post-operative leaks in patients undergoing a total gastrectomy. Post-operative leaks are a dangerous complication of the surgery, leading to stricture and possibly death. In a retrospective study, the technology was shown to reduce this complication by 75%.

December 9, 2014 - 2015 Deliver the Dream Schedule

Deliver the Dream will be hosting a series of retreats for families experiencing a serious illness. Each retreat is geared towards a specific illness or crisis providing families with resources and opportunities to network with others who are dealing with a similar situation.

December 7, 2014 - Gastric Cancer Survival Rate in India among the Lowest in the World

Some of the most advanced medical facilities in the world can be found in the city of Mumbai. Yet a study tracking cancer patients from 67 countries found that India's survival rate is low (19%) compared to other countries (25-30% on average). One of the authors cite a lack of equitable healthcare access to diagnose and treat patents as a possible explanation.

December 5, 2014 - Does an Aspirin a Day Really Keep the Doctor Away?

A study this year found that aspirin reduces the risk of certain digestive cancers. Aspirin works as an anti-inflammatory agent becoming an important preventative treatment against gastric cancer. However, it is best to assess personal risk and benefits with a health provider on the daily usage of aspirin.

December 3, 2014 - Long-Term Survival Rate Shows Little Improvement

A study led by the London School of Hygiene & Tropical Medicine analyzed cancer survival trends in England and Wales between 1971 and 2011. For gastric and esophageal cancers there has been little to no improvement in the long-term survival rate since the 1970's. The combination of latent symptoms and delayed diagnosis of these common digestive cancers limits the range of treatment which subsequently hinders the overall survival rate.

December 3, 2014 - Effective Treatment of Advanced Gastric Cancer

Investigators studied the combined drug therapy of docetaxel/oxaliplatin/5-fluorouracil (5-FU) for treatment against advanced gastric cancer. This combined regiment was compared to the standard chemotherapy treatment of docetaxel/oxaliplatin or docetaxel/oxaliplatin/capecitabine. It was concluded through the study that a lower adverse effect and higher tumor response rate were observed with the treatment of docetaxel/oxaliplatin/5-FU compared with the standard mode of care.

December 2, 2014 - Searching for a Trait

Sequencing the whole cancer genome is an effective yet costly tool when analyzing the efficacy of oncological drug treatment. Currently the technology is used to identify DNA alterations in a particular tumor with the goal to evolve the technology into a preventative tool.

December 2, 2014 - Should You Really Go For That Barbecue?

Nutritionists warn that cooking techniques involving high temperatures (over 150 degrees) cause the release of compounds perceived as toxic to human health. Known as polycyclic aromatic hydrocarbons (PAHs) and heterocyclic amines (HCAs), these compounds are shown to cause several types of cancer when repeatedly consumed. Experts recommend eating fried, roasted, and smoked foods in moderation to guard against cancer.

December 2, 2014 - Cimetidine Has Positive Effects Against Gastric Cancer

Cimetidine is an over-the-counter drug that is traditionally used to control indigestion by blocking histamine receptors in the gut, decreasing the production of gastric acid. The medicine also appears to block histamine receptors in cancer cells and support the immune system's defenses against cancer. Cimetidine has demonstrated positive effects in several cancers including gastric cancer.

December 2, 2014 - Garlic - National Institutes of Health (NIH) National Center for Complementary and Alternative Medicine (NCCAM)

Dietary benefits of garlic range from lowering cholesterol levels to slowing the development of atherosclerosis. Some studies suggest that garlic may lower the risk of certain cancers; currently a clinical trial shows no correlation between gastric cancer prevention and long term garlic consumption. It is important to disclose complementary health practices such as garlic consumption, as garlic compounds are known to interact with certain drugs.

December 1, 2014 - Fluorescence Microscopy: New 2-D Images Can Detect Cancer Risk

A new method studying protein concentrations found within gastric cells may help identify individuals who are at risk for hereditary diffuse gastric cancer (HDGC). This method can be used as a complementary approach to evaluate the risk of specific protein mutations that may lead to HDGC.

November 28, 2014 - First Targeted Treatment to Boost Survival for Esophageal Cancer

Gefitinib, an EGFR inhibitor, has yielded benefits for patients with a specific type of esophageal cancer. According to results presented at the 2014 NCRI, up to 1 in 6 patients with esophageal cancer have EGFR duplication and the use of Gefitinib increased their survival rates.

November 25, 2014 - Cancer Insurance Checklist

Open enrollment for the Health Insurance Marketplace is open from November 15-February 15. The Cancer Insurance Checklist can help you navigate your insurance needs by allowing you to create side-by-side comparisons of insurance plans, assist you in talking to insurance representatives and your health care provider all while taking into account your personal medical needs. Follow the link below to download a FREE copy now.

November 24, 2014 - Stomach Cancer and BRCA Gene Mutation Lead Patient to Take Action

Debbie's Dream Foundation PREP Mentor Melani Vincelli shared her experience working with doctors and surgeons and the importance of finding the right doctor-patient relationship. Melani was diagnosed with Stage IV gastric cancer five years ago, and as a carrier of the BRCA gene mutation she was considered high risk for developing breast cancer. After fighting cancer and recently undergoing prophylactic surgery Melani now raises her voice to spread awareness and lobby for funding.

November 24, 2014 - Peptic Ulcer, Cancer Bacteria Therapy Discovery

Linolenic acid, a common ingredient in vegetable oils, may help reduce infection with Helicobacter pylori. According to a study on mice, linolenic acid killed H. pylori, the bacteria associated with stomach cancer. Standard antibiotic therapy is effective, but alternative treatments are promising in the face of antibiotic resistance.

November 24, 2014 - Amgen Terminates Gastric Cancer Treatment Studies

Amgen Inc. announced that it has terminated all of its sponsored clinical trials of rilotumumab for advanced gastric cancer after an increased number of deaths were reported. All clinical studies have been stopped and data from each phase is currently undergoing analysis.

November 24, 2014 - Ronnie James Dio Stand Up and Shout Cancer Fund Donates $100,000 for Gastric Cancer Research

Founded in memory of the late singer, the Ronnie James Dio Stand Up and Shout Cancer Fund recently donated $100,000 to the T.J. Martell Foundation for Leukemia, Cancer and AIDS Research. The money will be used for the advancement of gastric cancer research at the Vanderbilt-Ingram Cancer Center. The Ronnie James Dio Foundation raises funds to stop cancer before it starts through early detection.

November 23, 2014 - Several Studies Show the European Mistletoe Can Help Various Types of Cancers

A study shows that the European mistletoe may be helpful for individuals with gastric cancer. The study concluded that patients experienced lower occurrences of diarrhea with the combination of mistletoe extract and oral chemotherapy.

November 22, 2014 - 12 Health Benefits of Broccoli

Scientists have found many health benefits associated with the consumption of broccoli such as detoxification, heart health, prevention of osteoarthritis, as well as being an anti-inflammatory and diet aid. Broccoli is also an anti-carcinogenic, containing compounds and nutrients known to guard against cancer. The vegetable is rich in glucoraphanin which can be used by the body to help prevent cancer and eliminate H. pylori, the bacteria associated with stomach cancer.

November 21, 2014 – Almonds Linked as Cancer Killer at BJU Research Lab

A cancer research lab is focusing on the almond's natural effect against cancer cells.  The research denotes that properties within the almonds lead to the destruction of cancerous cells. The almond research has not yielded a cure, but it may demonstrate the importance of nutrition.

November 21, 2014 - Top 10 Most Promising Drugs Guaranteed to Save Lives in 2015

The FDA has approved Cyramza for the treatment of metastatic stomach cancer. Cyramza has made the top 10 list of most promising drugs to save lives in the next year as compiled by Healthcare Global.

November 18, 2014 – Surgery Plus Chemoradiation Linked to Improved Survival Rates for Gastric Cancer Patients

In the last decade, chemoradiation therapy (both chemotherapy and radiation therapy) has improved making it an important tool to consider. In a retrospective study, patients who received chemoradiation after surgery appear to have increased survival rates.  Chemoradiation also showed an increase in recurrence-free survival rates.

November 15, 2014 - Milk Protein Used in Production of Drug Nanocarriers

Drugs that are currently used for the treatment of cancers, specially gastric cancer, have not been designed in a target delivery manner. Therefore, large amount of the drugs must be consumed during the treating process. In addition to its side effects, it causes patients with problems from financial point of view. Milk proteins have been used in the production of the nanocarrier. The production and evaluation of performance of the drug delivery system is at laboratorial stage at the moment.

November 06, 2014 - Extra Stomach Cancer Indications for Cyramza in US

The FDA has approved Cyramza in combination with paclitaxel chemotherapy as a second-line treatment option for patients with advanced gastric cancer or gastroesophageal junction adenocarcinoma. Cyramza is the only FDA-approved second-line treatment option for patients with this type of cancer.

November 5, 2014 - FDA Approves Cyramza Plus Paclitaxel for Gastric Cancer

The FDA has approved Lilly's Cyramza (ramucirumab) in combination with paclitaxel (a type of chemotherapy) as a treatment for patients with advanced or metastatic gastric or gastroesophageal junction adenocarcinoma whose cancer has progressed on or after prior fluoropyrimidine- or platinum-containing chemotherapy. The combination approval of of Cyramza follows its April approval as a single agent - the first for U.S. patients in this setting.

November 3, 2014 - Scott Loses 30 lbs and Brings Awareness to Curing Stomach Cancer Month

Our FitStar of the week is Scott Shirai from Boynton Beach, Florida. Scott has lost 30 pounds with the help of FitStar! He also is raising awareness about stomach cancer. November is Curing Stomach Cancer Month and Scott is helping lead the fight against it through his organization Debbie's Dream Foundation.

November 2, 2014 - Scientists Create Mini Human Stomach

A team of scientists in collaboration with researchers at the University of Cincinnati College of Medicine have created a miniature version of the human stomach using stem cells in order to study an infection caused by the H. pylori bacteria that causes peptic ulcers and stomach cancer. The 3-D mini stomachs allow the scientists to study the early stages of stomach cancer and its formation, as well as studying some of the basics of diabetes and obesity. The hope is that the research will lead to the development of new drugs and other treatments.

October 29, 2014 - FOLFIRI May be Viable First-Line Regimen for Advanced Gastric, EsophagoGastric Junction Adenocarcinoma

Patients with advanced gastric and esophagogastric junction adenocarcinoma who underwent first-line treatment with fluorouracil, leucovorin and irinotecan demonstrated significantly longer time to treatment failure than those treated with epirubicin, cisplatin and capecitabine, according to results of a randomized phase 3 study.

October 28, 2014 - Helicobacter pylori vaccine

ImevaX GmbH announced today that they will be funding a clinical trial of IMX 101, which is a highly specific vaccine against Helicobacter pylori (H. pylori). Chronic infections of the stomach with H. pylori are the most common bacterial infections worldwide and lead to gastritis, stomach ulcers and potentially stomach cancer. Due to the high global infection rate and the decreasing efficacy of existing antibiotics against H. pylori plus the poor safety profile of these treatments, there exists a high medical need and a significant commercial interest in a H. pylori vaccine.

October 24, 2014 - Soy, Allium Vegetables and Mushroom Prevent Cancer

In this study, high intake of soy products including soybean, soybean curd (tofu), and soymilk are linked to nearly 70% reduced risk of gastric cancer. Allium vegetables such as onion and garlic when used in high quantity were associated with 63% reduced risk for cancer, and high intake of mushroom was correlated with 57% reduced risk for gastric cancer.

October 24, 2014 - More Focus on H Pylori and Gastric Cancer Needed

Though uncertainties remain, gastric cancer and Helicobacter pylori represent an enormous opportunity for prevention. An amazing 770,000 out of 989,000 total gastric cancer cases around the world in 2008 can be attributed to the bacterial infection, suggesting that eradication could yield drastic reductions in incidence. Estimates suggest 700,000 people will die of gastric cancer this year, making it the third-most common cause of cancer deaths around the world.

October 14, 2014- AstraZeneca Looks To EU Decision For Next Cancer Drug Boost

Olaparib blocks an enzyme involved in cell repair and is designed for patients with certain hereditary gene mutations. It also has promise in treating breast and gastric cancers, opening up a substantial market opportunity.

October 5, 2014 - Green Tea Could Help Scientists Develop New Cancer Fighting Drugs

Scientists believe green tea could be used to develop new drugs to fight cancer. Green tea is made up of a class of chemicals called catechins, the most abundant of which is EGCG (Epigallocatechin Gallate). Dr Joo Eun Chung and his colleagues have shown that the anticancer protein Herceptin can combine with EGCG to form a stable and effective complex to deliver a drug to a tumor site.

September 28, 2014 - Merck Drug Extends Immune System Fight to Stomach Cancer

Merck & Co's drug Keytruda, the first in a new wave of immune-boosting medicines to be approved for treating melanomas in the United States, also has potential in stomach cancer, new research shows. Early clinical trial results reported on Sunday mean that gastric, or stomach cancer, can be added to a growing list of tumor types where so-called immunotherapy may have an important role to play.

September 26, 2014 - Treating an infection to prevent a cancer: H. pylori and stomach cancer

Nearly 11,000 Americans will likely die from gastric cancer this year, with only 28 percent of cases surviving five years or more. About 77 percent of gastric cancer cases are linked to chronic infections of Helicobacter pylori, a helix-shaped bacteria that was identified in the early 1980s and found to be linked to gastric ulcers a few years later, as well as to gastritis, an inflammation of the stomach lining that is a precursor to stomach cancer. Screening and treatment for H pylori is generally acceptable and affordable. An inexpensive serological test can determine who may be infected, with a sensitivity and specificity that could be sufficient for population-based prevention programs.

September 8, 2014 - Prediabetic Patients May Face Higher Risk for Stomach Cancer

Having too much sugar in your blood, even if you are not diabetic, is considered unhealthy and there may be an association between having high blood sugar levels and developing a serious health condition. Past research has suggested a possible link between prediabetes and cancer. The cancers most associated with prediabetes were liver, stomach/colorectal and uterine (endometrial) cancers. Talk to a dietician about ways to improve your diet. For more information on nutrition visit:

September 1, 2014 - Increased Helicobacter Pylori is Mediated by Spermine Oxidase

Helicobacter pylori infection causes gastric cancer, the third leading cause of cancer death worldwide. More than half of the world's population is infected. Clinical trials suggest that antibiotic treatment only reduces gastric cancer risk in patients with non-atrophic gastritis (NAG), and is ineffective once preneoplastic lesions of multifocal atrophic gastritis (MAG) and intestinal metaplasia (IM) have occurred. Polyamines, generated by the rate-limiting enzyme ornithine decarboxylase (ODC), in gastric carcinogenesis have been used as an additional strategy.

August 29, 2014 - Severing Nerves May Shrink Stomach Cancers

Research from Columbia University Medical Center shows that nerves may play a critical role in stomach cancer growth and that blocking nerve signals using surgery or Botox could be an effective treatment for the disease. The study was conducted by the laboratory of Timothy C. Wang, MD, in collaboration with Duan Chen, MD, PhD, in Norway and is published in an August issue of Science Translational Medicine. Using three different mouse models of stomach cancer, Dr. Wang's team found that when they performed a procedure called a vagotomy to cut the nerves, the surgery significantly slowed tumor growth and increased survival rates.

August 26, 2014 - Botox 'Highly Effective' Treatment of Gastric Cancer

In laboratory tests, Botox - made from the toxin of botulism bacteria - proved "highly effective" at suppressing gastric cancer in mice. The promising results have led to the launch of an early clinical trial involving human patients with stomach cancer in Norway. Botox injections are less toxic than most standard cancer treatments, caused hardly any side effects, and are relatively cheap.

August 24, 2014 - Drug of Choice

One of the cheapest drugs in the world is perhaps the most single effective agent in helping populations stay alive. The drug is aspirin. Aspirin can help with cardiovascular risk, stopping cancer, and the risk of bleeding among other things. Esophageal and stomach cancer rates were cut by thirty percent. Also, the death rate reduction exceeded the reduction in tumor incidence. That means the people who did get these tumors, if they were taking aspirin, lived longer.

August 10, 2014 - Results Demonstrate 'Ongoing Need For Improvement' In Gastric Cancer Treatment

Controversy about the required radicality of surgery in the curative treatment of gastric cancer has lessened in recent years. There is not a nearly global consensus that D2 lymphadenectomy represents the optimal surgery for gastric cancer. Read more on this article written by DDFs Medical Advisory Board Member, Dr. David Ilson.

August 8, 2014 - Cancer Should Be Classified By Genetic and Molecular Type

A research network in the US proposes that cancer should be classified according to genetic and molecular features rather than by the type of tissue in which the tumor arises. Scientists say that such a system would be better for patients because it would help tailor treatment to their individual needs. Medical News Today recently reported another TCGA study that found four distinct molecular subtypes of stomach cancer.

August 6, 2014 - Daily Aspirin Cuts Bowel and Stomach Cancer Deaths

Scientists have found that taking aspirin daily can significantly reduce the risk of developing, and dying from, the major cancers of the digestive tract, such as bowel, stomach and oesophageal cancer. Rates of oesophageal and stomach cancers were cut by 30 percent and deaths from these cancers by 35-50 percent according to the researchers led by Professor Jack Cuzick, Head of QMUL's Centre for Cancer Prevention.

August 5, 2014 - DNA Work Offers Stomach Cancer Hope

Doctors from the University of Hong Kong have mapped the world's most comprehensive DNA database showing hundreds of genetic mutations in stomach cancer. The DNA mapping could help develop "targeted" drugs for the disease. Currently there is only one such targeted drug, Herceptin, available to treat stomach cancer. The university team has identified hudreds of driver genes causing the disease.

July 30, 2014 - TCGA Identifies Four Gastric Cancer Subtypes

Researchers of The Cancer Genome Atlas Research Network have found that gastric adenocarcinomas can be divided into four distinct groups: tumors that are positive for Epstein-Barr Virus; microsatellite unstable unstable tumors; genomically stable tumors; and tumors with chromosomal instability. The researchers, led by Adam Bass, MD, of Dana-Farber Cancer Institute in Boston, obtained samples of adenocarcinoma from 295 patients who had not been treated with prior chemotherapy or radiotherapy. They conducted a variety of genomic analyses, including whole genomic sequencing on 107 tumor/germline pairs. Bass says that a key advance in this project is the development of a much more useful classification system, which will allow doctors to pursue key targets in different groups of patients.

July 25, 2014 - MGr1-Ag/37LRP Promotes Growth and Proliferation of Gastric Cancer in Vitro and in Vivo

Gastric carcinoma (GC) is an aggressive cancer due to the MGr1-Ag cells that make up the many tissues of the stomach. MGr1-Ag was originally thought to resist the many drugs used to combat this lethal cancer. Since the MGr1-Ag is very common in GC tissues and not healthy tissues, the outlook looked grim. However, recent studies suggest that tumor growth is dependent on a certain region within the MGr1-Ag and the knockdown of this certain type of cell leads to decreased GC cell growth in vivo and in vitro. These studies can potentially be used as a prognostic factor and a therapeutic target for GC.

July 23, 2014 - Debbie's Dream Foundation Continues to Be at the Forefront of Hastening Stomach Cancer Treatment Development and Assisting with Clinical Trials Enrollment

Debbie's Dream Foundation is contributing to the fight against stomach cancer on many fronts. We are very proud of our DDF Medical Advisory Board Member Adam Bass and his leadership on the TCGA Gastric Cancer Project. This project is a federally funded initiative that involves large international groups of researchers and centers that are cataloging genomic characteristics in gastric (stomach) cancer. The project, which announced its findings in Nature today, found that there are four main subtypes of stomach cancer. This revolutionary finding of gastric cancer subtypes is expected to lead to quicker improvements in the diagnosis, treatment and prevention of stomach cancer.

July 17, 2014 - Local Scientists Find Out What Turns Stomach Cells Cancerous

Instead of carrying cancer-causing mutations in genes, researchers in Singapore found that stomach cancer cells have normal genes that are being abnormally activated, which causes the cells to turn cancerous. Using the latest DNA sequencing technologies developed at their institute, the tumor cells are comprehensively analyzed to identify molecular differences between cancer cells and normal tissue. Data from the World Health Organization showed that stomach cancer is a major cause of cancer death worldwide.

July 15, 2014 - Assessing the 'Fit' Older Patient for Chemotherapy

Making appropriate treatment decisions for older adults with cancer is one of the most important challenges that oncologists face in daily practice, as the therapy selected depends on an assessment of the patient's "fitness." In this article you will find specific considerations for evaluating patients who appear to be "fit" for chemotherapy treatment, and outline methods for integrating the principles of geriatric medicine to form a clear picture of an older adult's level of fitness and thus his or her individual risk of significant toxicity from cancer therapy.

July 14, 2014 - 5 Eating Habits That Can End In Stomach Cancer

Here are five unhealthy diets that can make us vulnerable to stomach cancer: irregular diet, hot and stimulating foods, 'distracted diet', rice soaked with soup, and acidic fruit on an empty stomach. People who have irregular diets suffer 1.3 times the incidence of stomach cancer than those who eat at a fixed time. Hot food increases the risk of the stomach cancer by 4.22 times. Suggestions offered by medical experts are that it would help if we get up 15 to 20 minutes earlier and focus on breakfast, rather than to eat on the go. Eating rice that has been soaked with soup increases the burden in the stomach since the rice has been swallowed whole. When we are hungry, gastric acid in the stomach will reach a high concentration, which, if combined with fruit, will precipitate in the stomach.

July 10, 2014 - Phase I Trial for BeiGene's PARP Inhibitor Begins

The first patient has been dosed in the Phase I trial of BGB-290 for cancer treatment. BGB-290 is an inhibitor of PARP, an enzyme that is involved in multiple cell processes. Small molecules of BGB-290 have shown to fight tumors by picking up and trapping PARP proteins on damaged DNA. Anti-tumor effects have been exhibited and could become a treatment option for common cancers.

July 4, 2014 - Researchers Discover Novel Protein Complex with Potential to Combat Gastric Cancer Caused By Bacterial Infection

Scientists from the Cancer Science Institute of Singapore (CSI Singapore) discovered that a protein named IL23A is part of our stomach's defense against bacterial infection which leads to gastric cancer. This finding could potentially be used to combat the deadly disease. In Singapore, stomach cancer was the fourth leading cause of cancer death among men and fifth among women from 2008 to 2012. This highlights the urgent need to understand the causes of this deadly disease.

July 2, 2014 - Apatinib Prolongs Survival in Advanced Gastric Cancer

Apatinib significantly improved overall survival according to the results of a phase III study presented at the 2014 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. Results of the study revealed an almost 2-month overall survival advantage for patients assigned to treatment with apatinib.Treatment with apatinib was generally well tolerated and the main side effects consisted of low white blood cell counts, low platelet counts and toxicity to the skin know as hand-foot syndrome.

June 28, 2014 - Dr. Bendell Discusses a Phase III Study of Apatinib in Gastric Cancer

Johanna Bendell, MD, director of GI Cancer Research Program discusses a randomized phase III placebo-controlled trial that explored apatinib as a treatment for patients with advanced gastric cancer. During the trial, the drug was studied in Chinese patients as second-line therapy for patients with metastatic gastric cancer. The study found that there was a statistically significant improvement in overall survival in the apatinib arm versus the placebo arm, Bendell says.

June 27, 2014 - Ramucirumab Benefit for US Patients With Gastric Cancer Mirrors Global Results

Patients in the United States and other Western nations experienced similar survival gains and adverse events as did their counterparts in two other regions of the world from the use of ramucirumab (Cyramza) in advanced gastric cancer. Eli Lilly and Company, which developed the drug, supported this geographic analysis of clinical trial results.

June 25, 2014 - Advaxis Gets Allowance from USPTO for Two Cancer Immunotherapy Patent Applications

ADXS-cHER2 is being developed to target the Her2 receptor, which is overexpressed in certain solid-tumor cancers, including bone cancer (osteosarcoma), breast cancer, esophageal and gastric cancer. Advaxis, a United States based clinical-stage biotechnology firm is planning to start a Phase I trial with ADXS-cHER2 in pediatric osteosarcoma, for which it received orphan drug designation, and is pursuing early development clinical collaborations for breast, esophageal and gastric cancers.

June 25, 2014 - Nigeria: Heartburn Can Lead to Ulcers, Stomach Cancer

Gastro-Esophageal Reflux Disease (GERD), also referred to as heart burn, has been warned as a serious medical condition according to Nigerian medical experts. Apart from discomfort and pain associated with the condition, it can eventually lead to ulcers, stomach cancer and cancer of the oesophagus.

June 25, 2014 - Diet Poses Big Cancer Risk

Your diet says a lot about your future.  Among the top 10 cancers that threaten Chinese people's health, five are cancers of the digestive system, including esophageal cancer, gastric cancer and colorectal cancer.  Experts remind citizens to change their unhealthy dietary patterns and eat more fruits and vegetables, the Beijing Morning Post reported.  What are you eating?

June 25, 2014 - Diet Poses Big Cancer Risk

Your diet says a lot about your future. Among the top 10 cancers that threaten Chinese people's health, five are cancers of the digestive system, including esophageal cancer, gastric cancer and colorectal cancer. Experts remind citizens to change their unhealthy dietary patterns and eat more fruits and vegetables, the Beijing Morning Post reported. What are you eating?

June 24, 2014 - Stomach Cancer Treatment Advances at Memorial Sloan Kettering

Memorial Sloan Kettering is one of the leading cancer centers in the United States for diagnosing and treating patients with stomach cancer. Their effectiveness in treating this disease has been enhanced by the ability to identify subtle but important differences among various types of stomach cancer and to accurately stage the condition so that they can determine the best treatment approach. Memorial Sloan Kettering's multidisciplinary team of more than 20 doctors includes world-class specialists in gastroenterology, surgical oncology, medical oncology, interventional radiology, and radiation oncology who work closely together to diagnose and treat this illness.

June 23, 2014 - H.Pylori is the deadliest thing you've never heard of - here's why you should be screened for it

Helicobacter Pylori (H.Pylori) is a common bacterial infection of the lining of the stomach. H.Pylori often causes no symptoms but is associated with a number of significant conditions such as stomach cancer. It is estimated that 2500 new cases of stomach cancer occurring within the UK each year are linked to the presence of H.Pylori infection. Screening for H.Pylori, perhaps as part of a full health check or health assessment, can reduce the risk of developing stomach cancer by one-third. Ask your doctor at your next visit!

June 20, 2014 - Cancer Patients May 'Feel Drunk' From Docetaxel, Says FDA

The commonly used intravenous chemotherapy docetaxel "may cause patients to experience intoxication or feel drunk during and after treatment," warns the US Food and Drug Administration (FDA). The FDA is revising the labels of all docetaxel products to warn about the risk for intoxication.Docetaxel is used in the treatment of cancers of the breast, prostate, stomach, head and neck, and lung.

June 16, 2014 - Basket Design: A Novel Approach to Cancer Clinical Trials

The growing understanding of cancer biology has demanded that the design of cancer clinical trials evolves as well. One example of this is the "basket trial" design mentioned numerous times throughout the ASCO 2014 meeting. This novel study design attempts to match patients with a rare mutation, regardless of tumor histology, to a drug expected to work through the mutated pathway.

June 14, 2014 - Genetic mutation behind inherited stomach cancer

A genetic mutation was discovered by researchers at Otago University, led by Parry Guilford, that is linked to inherited stomach cancer. The gene is rare, known in only about 350 families worldwide. Once the gene is found, one must decide whether to live with the mutation or to have their stomach removed by total gastrectomy.

June 13, 2014 - June is Men's Health Month

Celebrate every June, Men's Health Month! Men's Health Month is celebrated across the country with screenings, health fairs, media appearances, and other health education and outreach activities. 55 percent of men have not seen their doctor in the past year, and men make half as many doctors visits for prevention as women. Lets celebrate this month of awareness for men's health!

June 10, 2014 - Immune Protein Could Fight Gastric Cancer

In recent gastric cancer studies, scientists have found that a protein called IL23A could help in the fight against stomach cancer. This protein is secreted by white blood cells in response the bacterial infection H. pylori. However, IL23A can only be expressed if RUNX3,a tumor suppressor gene, is present. In gastric cancer patients this gene is commonly suppressed. However, by tapping into RUNX3's potential, IL23A could help in the fight against stomach cancer.

June 10, 2014 - Cancer Council takes aim at lesser-known killers such as stomach cancer

The Cancer Council plans to shine the spotlight on the- -"forgotten cancers" such as stomach, liver, and pancreas cancer. These cancers are responsible for more than half of all cancer deaths in Australia. The Cancer Council's Forgotten Cancers Project will look into the causes of less common cancers and try to increase early detection and survival rates.

June 5, 2014 - FOLFOX Plus Ramucirumab Fails to Improve PFS in Gastric, Esophageal Cancer

A phase II trial was presented at the 2014 American Society of Clinical Oncology (ASCO) Annual Meeting showing that adding ramucirumab to FOLFOX did not delay progression in patients with untreated advanced gastric or esophageal adenocarcinoma. However, the anti-VEGFR2 monoclonal antibody was found to improve disease control rate, and to provide a longer progression-free survival in a subgroup of patients with gastric or gastroesophageal junction adenocarcinoma.

June 3, 2014 - Chinese Study on Advanced Gastric Cancer Cure Wins American Award

Every year around 952,000 new gastric cancer cases are diagnosed worldwide and 47 percent of those are in China. 60 to 80 percent of those diagnosed are diagnosed at a late stage, which leaves them with very limited treatment options. Chinese doctors have recently won an award for their new study on the treatment of advanced gastric cancer which they presented at the American Society of Clinical Oncology (ASCO) in Illinois.

June 3, 2014 - Red meat's a tasty treat but too much can give you cancer

Recent research from China has found that a diet of just 100 grams of red meat per day increases the risk of stomach cancer by 17%. The department of health recommends a diet consisting of only 65 grams of cooked red meat per day.

June 3, 2014 - Positive tips for making chemotherapy a little less miserable

Positive tips for making chemotherapy a little less miserable. Read these tips from Amanda Woodward who receives her chemotherapy at MD Anderson.

May 29, 2014 - H. pylori eradication failed to reduce risk for gastric cancer after resection

According to a trial held in Seoul, South Korea from 2005 to 2011 eradication of Helicobacter Pylori did not reduce the patients risk of developing stomach cancer. 901 patients with H. Pylori who had been treated with endoscopic resection for early gastric cancer or gastric dysplasia were used as a part of this trial.

May 19, 2014 - Food Consumer

Eating too much red meat like beef may increase risk of stomach cancer, a study released in the June 2014 issue of Journal of Cancer Research and Clinical Oncology suggests. Population based case-control studies showed that high red meat consumption was associated with 58% increased risk of stomach cancer, compared with low consumption.

May 15, 2014 - News Medical About Diagnosing Stomach Cancer

Scientists from the University of Granada have successfully created magnetic bacteria that could be added to foodstuffs and could, after ingestion, help diagnose diseases of the digestive system like stomach cancer. These important findings constitute the first use of a food as a natural drug and aid in diagnosing an illness, anywhere in the world.

May 4, 2014 - International Nurses Week 2014: Have You Thanked A Nurse For Their Hard Work?

The week of May 6 - May 12 each year is National Nurses Week in the U.S. Florence Nightingale, born in 1820, made a name for herself after taking charge of nursing British and allied soldiers in Turkey during the Crimean War. She worked hours upon hours, tending to soldiers day and night. She changed nursing from the verge of incompetency, widely influencing practices such as sanitation, military health, and hospital planning. To this day, many of her practices are still implemented in hospitals worldwide, and the nurses are just as hardworking too. In commemoration of them, International Nurses Week will begin on Tuesday, and end on Nightingale's birthday, May 12.

May 1, 2014 - Gastric Cancer

It is estimated that 22,220 new cases of gastric cancer will be diagnosed in the United States in the year 2014, with 10,990 deaths expected. Worldwide in 2012, gastric cancer developed in approximately 930,000 individuals annually, accounting for 10% of neoplastic deaths. If you or a loved one has been diagnosed with gastric cancer, this article breaks down a total overview of important information that you need to know.

January 22, 2014 - Cooking Up Cancer?

A growing body of research suggests that cooking meats over a flame is linked to cancer. Combusting wood, gas, or charcoal emits chemicals known as polycyclic aromatic hydrocarbons. Exposure to these so-called PAHs is known to cause skin, liver, stomach, and several other types of cancer in lab animals. Epidemiological studies link occupational exposure to PAHs to cancer in humans.